A non-randomized trial to assess the safety, tolerability, and pharmacokinetics of posaconazole oral suspension in immunocompromised children with neutropenia

BACKGROUND: Posaconazole (POS) is a potent triazole antifungal agent approved in adults for treatment and prophylaxis of invasive fungal infections (IFIs). The objectives of this study were to evaluate the pharmacokinetics (PK), safety, and tolerability of POS oral suspension in pediatric subjects w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Arrieta, Antonio C., Sung, Lillian, Bradley, John S., Zwaan, C. Michel, Gates, Davis, Waskin, Hetty, Carmelitano, Patricia, Groll, Andreas H., Lehrnbecher, Thomas, Mangin, Eric, Joshi, Amita, Kartsonis, Nicholas A., Walsh, Thomas J., Paschke, Amanda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435162/
https://ncbi.nlm.nih.gov/pubmed/30913226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212837
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