High prevalence of Pfdhfr–Pfdhps quadruple mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from Bioko Island, Equatorial Guinea

BACKGROUND: Sulfadoxine–pyrimethamine (SP) is recommended for intermittent preventive treatment of malaria in Africa. However, increasing SP resistance (SPR) affects the therapeutic efficacy of the SP. As molecular markers, Pfdhfr (dihydrofolate reductase) and Pfdhps (dihydropteroate synthase) genes...

詳細記述

保存先:
書誌詳細
出版年:Malar J
主要な著者: Jiang, Tingting, Chen, Jiangtao, Fu, Hongxia, Wu, Kai, Yao, Yi, Eyi, Juan Urbano Monsuy, Matesa, Rocio Apicante, Obono, Maximo Miko Ondo, Du, Weixing, Tan, Huabing, Lin, Min, Li, Jian
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434785/
https://ncbi.nlm.nih.gov/pubmed/30914041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2734-x
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