Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell–Mediated Hepatitis via Compensatory Up-regulation of CXCR2–Related Chemokine Activity

BACKGROUND & AIMS: Chemokine-mediated immune cell recruitment plays pivotal roles in liver inflammation. C-C motif chemokine ligand 5 (CCL5) has been shown to be responsible for the recruitment of monocytes/macrophages and has been implicated in various liver diseases, including nonalcoholic fat...

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Veröffentlicht in:Cell Mol Gastroenterol Hepatol
Hauptverfasser: Chen, Lili, Gu, Jinyang, Qian, Yihan, Li, Meng, Qian, Yongbing, Xu, Min, Li, Jichang, Wen, Yankai, Xia, Lei, Li, Jiaxin, Xia, Qiang, Kong, Xiaoni, Wu, Hailong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434496/
https://ncbi.nlm.nih.gov/pubmed/30630119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2018.12.009
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