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The downregulation of WWOX induces epithelial–mesenchymal transition and enhances stemness and chemoresistance in breast cancer

WW domain-containing oxidoreductase (WWOX), an important tumor suppressor, is essential for regulating cell proliferation and apoptosis. Our study demonstrates that low level of WWOX is associated with the triple-negative subtype of breast cancer (TNBC), which has higher stem cell phenotype and chem...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Li, Juan, Liu, Jie, Li, Pingping, Zhou, Can, Liu, Peijun
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434457/
https://ncbi.nlm.nih.gov/pubmed/30335523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370218806455
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