Simvastatin provides long‐term improvement of left ventricular function and prevents cardiac fibrosis in muscular dystrophy

Duchenne muscular dystrophy (DMD), caused by absence of the protein dystrophin, is a common, degenerative muscle disease affecting 1:5000 males worldwide. With recent advances in respiratory care, cardiac dysfunction now accounts for 50% of mortality in DMD. Recently, we demonstrated that simvastati...

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Bibliografske podrobnosti
izdano v:Physiol Rep
Main Authors: Kim, Min J., Bible, Kenneth L., Regnier, Michael, Adams, Marvin E., Froehner, Stanley C., Whitehead, Nicholas P.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434171/
https://ncbi.nlm.nih.gov/pubmed/30912308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14018
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