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ZEB1 protects skeletal muscle from damage and is required for its regeneration
The mechanisms linking muscle injury and regeneration are not fully understood. Here we report an unexpected role for ZEB1 regulating inflammatory and repair responses in dystrophic and acutely injured muscles. ZEB1 is upregulated in the undamaged and regenerating myofibers of injured muscles. Compa...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6434033/ https://ncbi.nlm.nih.gov/pubmed/30910999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08983-8 |
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