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Investigating the Connection Between Endogenous Heme Accumulation and COX2 Activity in Cancer Cells

Heme, an iron-containing porphyrin, is fundamental for a variety of functions in cell homeostasis. Nevertheless, recent data indicate that dysregulation of heme metabolism might promote tumorigenesis. The intracellular heme pool is finely regulated through the control of heme synthesis, degradation,...

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Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Destefanis, Francesca, Fiorito, Veronica, Altruda, Fiorella, Tolosano, Emanuela
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433962/
https://ncbi.nlm.nih.gov/pubmed/30941311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00162
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