Pore-forming protein complexes from Pleurotus mushrooms kill western corn rootworm and Colorado potato beetle through targeting membrane ceramide phosphoethanolamine

Aegerolysins ostreolysin A (OlyA) and pleurotolysin A (PlyA), and pleurotolysin B (PlyB) with the membrane-attack-complex/perforin domain are proteins from the mushroom genus Pleurotus. Upon binding to sphingomyelin/cholesterol-enriched membranes, OlyA and PlyA can recruit PlyB to form multimeric bi...

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Udgivet i:Sci Rep
Main Authors: Panevska, Anastasija, Hodnik, Vesna, Skočaj, Matej, Novak, Maruša, Modic, Špela, Pavlic, Ivana, Podržaj, Sara, Zarić, Miki, Resnik, Nataša, Maček, Peter, Veranič, Peter, Razinger, Jaka, Sepčić, Kristina
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433908/
https://ncbi.nlm.nih.gov/pubmed/30911026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41450-4
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