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Tanycyte-Independent Control of Hypothalamic Leptin Signaling

Leptin is secreted by adipocytes to regulate appetite and body weight. Recent studies have reported that tanycytes actively transport circulating leptin across the brain barrier into the hypothalamus, and are required for normal levels of hypothalamic leptin signaling. However, direct evidence for l...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Yoo, Sooyeon, Cha, David, Kim, Dong Won, Hoang, Thanh V., Blackshaw, Seth
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433882/
https://ncbi.nlm.nih.gov/pubmed/30941008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00240
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