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Polymorphism in Cytochrome P450 3A4 Is Ethnicity Related

Can mutations in Cytochrome P450 3A4 (CYP3A4), the major food- and drug-metabolizing enzyme, serve as biomarkers for personalized precise medicine? Classical genetic studies provide only limited data regarding the frequencies of CYP3A4 mutations and their role in food–drug interactions. Here, in an...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Guttman, Yelena, Nudel, Adi, Kerem, Zohar
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433705/
https://ncbi.nlm.nih.gov/pubmed/30941162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00224
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