Opposite effects of cannabinoid CB(1) and CB(2) receptors on antipsychotic clozapine‐induced cardiotoxicity

BACKGROUND AND PURPOSE: Clozapine is an atypical antipsychotic drug that is very efficacious in treating psychosis, but the risk of severe cardiotoxicity limits its clinical use. The present study investigated the harmful effects of clozapine on myocardium and assessed the involvement of cannabinoid...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Li, Liliang, Dong, Xiaoru, Tu, Chunyan, Li, Xiaoqing, Peng, Zhao, Zhou, Yiling, Zhang, Dingang, Jiang, Jieqing, Burke, Allen, Zhao, Ziqin, Jin, Li, Jiang, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433645/
https://ncbi.nlm.nih.gov/pubmed/30707759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14591
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