Opposite effects of cannabinoid CB(1) and CB(2) receptors on antipsychotic clozapine‐induced cardiotoxicity

BACKGROUND AND PURPOSE: Clozapine is an atypical antipsychotic drug that is very efficacious in treating psychosis, but the risk of severe cardiotoxicity limits its clinical use. The present study investigated the harmful effects of clozapine on myocardium and assessed the involvement of cannabinoid...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: Li, Liliang, Dong, Xiaoru, Tu, Chunyan, Li, Xiaoqing, Peng, Zhao, Zhou, Yiling, Zhang, Dingang, Jiang, Jieqing, Burke, Allen, Zhao, Ziqin, Jin, Li, Jiang, Yan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433645/
https://ncbi.nlm.nih.gov/pubmed/30707759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14591
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