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Aspirin eugenol ester attenuates oxidative injury of vascular endothelial cells by regulating NOS and Nrf2 signalling pathways

BACKGROUND AND PURPOSE: Aspirin eugenol ester (AEE) is a new drug compound synthesized by combining aspirin with eugenol. It was reported to possess anti‐thrombotic, anti‐atherosclerotic, and anti‐oxidative effects. However, its molecular mechanism against oxidative injury is unclear. This study inv...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Huang, Mei‐Zhou, Yang, Ya‐Jun, Liu, Xi‐Wang, Qin, Zhe, Li, Jian‐Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433644/
https://ncbi.nlm.nih.gov/pubmed/30706438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14592
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