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Aspirin eugenol ester attenuates oxidative injury of vascular endothelial cells by regulating NOS and Nrf2 signalling pathways

BACKGROUND AND PURPOSE: Aspirin eugenol ester (AEE) is a new drug compound synthesized by combining aspirin with eugenol. It was reported to possess anti‐thrombotic, anti‐atherosclerotic, and anti‐oxidative effects. However, its molecular mechanism against oxidative injury is unclear. This study inv...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Huang, Mei‐Zhou, Yang, Ya‐Jun, Liu, Xi‐Wang, Qin, Zhe, Li, Jian‐Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433644/
https://ncbi.nlm.nih.gov/pubmed/30706438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14592
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