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Sustained exposure to prostaglandin D(2) augments the contraction induced by acetylcholine via a DP(1) receptor-mediated activation of p38 in bronchial smooth muscle of naive mice

Prostaglandin D(2) (PGD(2)), one of the key lipid mediators of allergic airway inflammation, is increased in the airways of asthmatics. However, the role of PGD(2) in the pathogenesis of asthma is not fully understood. In the present study, effects of PGD(2) on smooth muscle contractility of the air...

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發表在:J Smooth Muscle Res
Main Authors: Suto, Wataru, Sakai, Hiroyasu, Chiba, Yoshihiko
格式: Artigo
語言:Inglês
出版: Japan Society of Smooth Muscle Research 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433600/
https://ncbi.nlm.nih.gov/pubmed/30918168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1540/jsmr.55.1
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