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Sustained exposure to prostaglandin D(2) augments the contraction induced by acetylcholine via a DP(1) receptor-mediated activation of p38 in bronchial smooth muscle of naive mice

Prostaglandin D(2) (PGD(2)), one of the key lipid mediators of allergic airway inflammation, is increased in the airways of asthmatics. However, the role of PGD(2) in the pathogenesis of asthma is not fully understood. In the present study, effects of PGD(2) on smooth muscle contractility of the air...

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Bibliographische Detailangaben
Veröffentlicht in:J Smooth Muscle Res
Hauptverfasser: Suto, Wataru, Sakai, Hiroyasu, Chiba, Yoshihiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Japan Society of Smooth Muscle Research 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433600/
https://ncbi.nlm.nih.gov/pubmed/30918168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1540/jsmr.55.1
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