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Prostaglandin D(2) Induces Ca(2+) Sensitization of Contraction without Affecting Cytosolic Ca(2+) Level in Bronchial Smooth Muscle

Prostaglandin D(2) (PGD(2)) is one of the key lipid mediators of allergic airway inflammation, including bronchial asthma. However, the role of PGD(2) in the pathogenesis of asthma is not fully understood. In the present study, the effect of PGD(2) on smooth muscle contractility of the airways was d...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Suto, Wataru, Ando, Yusuke, Hirabayashi, Takahiro, Takenoya, Fumiko, Shioda, Seiji, Kamei, Junzo, Sakai, Hiroyasu, Chiba, Yoshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213397/
https://ncbi.nlm.nih.gov/pubmed/30301147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103036
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