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Liver X receptors in lipid signalling and membrane homeostasis

Liver X receptors α and β (LXRα and LXRβ) are nuclear receptors with pivotal roles in the transcriptional control of lipid metabolism. Transcriptional activity of LXRs is induced in response to elevated cellular levels of cholesterol. LXRs bind to and regulate the expression of genes that encode pro...

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Detalhes bibliográficos
Publicado no:Nat Rev Endocrinol
Main Authors: Wang, Bo, Tontonoz, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433546/
https://ncbi.nlm.nih.gov/pubmed/29904174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41574-018-0037-x
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