Mitophagy reduces oxidative stress via Keap1/Nrf2/PHB2 pathway after SAH in rats

BACKGROUND AND PURPOSE—: Mitoquinone (MitoQ) has been reported as a mitochondria-targeting antioxidant to promote mitophagy in various chronic diseases. Here, our aim was to study the role of MitoQ in mitophagy activation and oxidative stress-induced neuronal death reduction after subarachnoid hemor...

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Pubblicato in:Stroke
Autori principali: Zhang, Tongyu, Wu, Pei, Budbazar, Enkhjargal, Zhu, Qiquan, Sun, Chengmei, Mo, Jun, Peng, Jianhua, Gospodarev, Vadim, Tang, Jiping, Shi, Huaizhang, Zhang, John H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433519/
https://ncbi.nlm.nih.gov/pubmed/30890112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.118.021590
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