NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin

Diabetic nephropathy (DN) is a microvascular complication of diabetes mellitus that results in both tubular and glomerular injury. Low-grade inflammation and oxidative stress are two mechanisms known to drive the progression of DN. Nucleotide-binding leucine-rich repeat containing family member X1 (...

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Udgivet i:PLoS One
Main Authors: Scantlebery, Angelique M. L., Uil, Melissa, Butter, Loes M., Poelman, Renée, Claessen, Nike, Girardin, Stephen E., Florquin, Sandrine, Roelofs, Joris J. T. H., Leemans, Jaklien C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433286/
https://ncbi.nlm.nih.gov/pubmed/30908533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214437
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