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A Late Phase of Long-Term Synaptic Depression in Cerebellar Purkinje Cells Requires Activation of MEF2

The MEF2 family of transcription factors restricts excitatory synapse number in an activity-dependent fashion during development, yet MEF2 has not been implicated in long-term synaptic depression (LTD), which is thought to initiate synapse elimination. Mutations in MEF2 pathways are implicated in au...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Andzelm, Milena M., Vanness, Devorah, Greenberg, Michael E., Linden, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433166/
https://ncbi.nlm.nih.gov/pubmed/30699340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.01.004
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