Anti-PD1 up-regulates PD-L1 expression and inhibits T-cell lymphoma progression: possible involvement of an IFN-γ-associated JAK-STAT pathway

PURPOSE: NK/T-cell neoplasms are rare, highly aggressive, and insensitive to chemotherapy. These lymphomas have a poor prognosis, with patients being vulnerable to relapse. Hence, there is a need for alternative treatments. The purpose of this study is to investigate whether anti-PD1 takes effect on...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Onco Targets Ther
Prif Awduron: Xue, Weili, Li, Weiming, Zhang, Tiantian, Li, Zhaoming, Wang, Yingjun, Qiu, Yajuan, Wang, Yuanyuan, Chen, Changying, Fu, Dongjun, Zhang, Mingzhi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2019
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433108/
https://ncbi.nlm.nih.gov/pubmed/30962691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S187280
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