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A complex between phosphatidylinositol 4-kinase IIα and integrin α3β1 is required for N-glycan sialylation in cancer cells

Aberrant N-glycan sialylation of glycoproteins is closely associated with malignant phenotypes of cancer cells and metastatic potential, which includes cell adhesion, migration, and growth. Recently, phosphatidylinositol 4-kinase IIα (PI4KIIα), which is localized to the trans-Golgi network, was iden...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Isaji, Tomoya, Im, Sanghun, Kameyama, Akihiko, Wang, Yuqin, Fukuda, Tomohiko, Gu, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433072/
https://ncbi.nlm.nih.gov/pubmed/30659093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005208
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