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Expression of N-Acetylglucosaminyltransferase III Suppresses α2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to α2,6-Sialylation Levels

N-Acetylglucosaminyltransferase III (GnT-III), which catalyzes the addition of the bisecting GlcNAc branch on N-glycans, is usually described as a metastasis suppressor. Overexpression of GnT-III inhibited migration in multiple types of tumor cells. However, these results seem controversial to the c...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lu, Jishun, Isaji, Tomoya, Im, Sanghun, Fukuda, Tomohiko, Kameyama, Akihiko, Gu, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786709/
https://ncbi.nlm.nih.gov/pubmed/26801611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.712836
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