Interleukin-18 up-regulates amino acid transporters and facilitates amino acid–induced mTORC1 activation in natural killer cells

Upon inflammation, natural killer (NK) cells undergo metabolic changes to support their high energy demand for effector function and proliferation. The metabolic changes are usually accompanied by an increase in the expression of nutrient transporters, leading to increased nutrient uptake. Among var...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Almutairi, Saeedah Musaed, Ali, Alaa Kassim, He, William, Yang, Doo-Seok, Ghorbani, Peyman, Wang, Lisheng, Fullerton, Morgan D., Lee, Seung-Hwan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433059/
https://ncbi.nlm.nih.gov/pubmed/30696773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005892
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