The Concerted Action of E2-2 and HEB Is Critical for Early Lymphoid Specification

The apparition of adaptive immunity in Gnathostomata correlates with the expansion of the E-protein family to encompass E2-2, HEB, and E2A. Within the family, E2-2 and HEB are more closely evolutionarily related but their concerted action in hematopoiesis remains to be explored. Here we show that th...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Bouderlique, Thibault, Peña-Pérez, Lucia, Kharazi, Shabnam, Hils, Miriam, Li, Xiaoze, Krstic, Aleksandra, De Paepe, Ayla, Schachtrup, Christian, Gustafsson, Charlotte, Holmberg, Dan, Schachtrup, Kristina, Månsson, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433000/
https://ncbi.nlm.nih.gov/pubmed/30936870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00455
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