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Exogenous lysyl oxidase-like 2 and perfusion culture induce collagen crosslink formation in osteogenic grafts

Lysyl oxidase (LOX)-mediated collagen crosslinking can regulate osteoblastic phenotype and enhance mechanical properties of tissues, both areas of interest in bone tissue engineering. The objective of this study was to investigate the effect of lysyl oxidase-like 2 (LOXL2) on osteogenic differentiat...

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Pubblicato in:Biotechnol J
Autori principali: Mitra, Debika, Yasui, Osamu W., Harvestine, Jenna N., Link, Jarrett M., Hu, Jerry C., Athanasiou, Kyriacos A., Leach, J. Kent
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432926/
https://ncbi.nlm.nih.gov/pubmed/30052320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201700763
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