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Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases

A hallmark event in neurodegenerative diseases (NDs) is the misfolding, aggregation, and accumulation of proteins, leading to cellular dysfunction, loss of synaptic connections, and brain damage. Despite the involvement of distinct proteins in different NDs, the process of protein misfolding and agg...

詳細記述

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書誌詳細
出版年:Nat Neurosci
主要な著者: Soto, Claudio, Pritzkow, Sandra
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432913/
https://ncbi.nlm.nih.gov/pubmed/30250260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0235-9
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