Modular systems metabolic engineering enables balancing of relevant pathways for l-histidine production with Corynebacterium glutamicum

BACKGROUND: l-Histidine biosynthesis is embedded in an intertwined metabolic network which renders microbial overproduction of this amino acid challenging. This is reflected in the few available examples of histidine producers in literature. Since knowledge about the metabolic interplay is limited,...

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Detaylı Bibliyografya
Yayımlandı:Biotechnol Biofuels
Asıl Yazarlar: Schwentner, Andreas, Feith, André, Münch, Eugenia, Stiefelmaier, Judith, Lauer, Ira, Favilli, Lorenzo, Massner, Christoph, Öhrlein, Johannes, Grund, Bastian, Hüser, Andrea, Takors, Ralf, Blombach, Bastian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432763/
https://ncbi.nlm.nih.gov/pubmed/30962820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-019-1410-2
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