Modular systems metabolic engineering enables balancing of relevant pathways for l-histidine production with Corynebacterium glutamicum

BACKGROUND: l-Histidine biosynthesis is embedded in an intertwined metabolic network which renders microbial overproduction of this amino acid challenging. This is reflected in the few available examples of histidine producers in literature. Since knowledge about the metabolic interplay is limited,...

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Detalhes bibliográficos
Publicado no:Biotechnol Biofuels
Main Authors: Schwentner, Andreas, Feith, André, Münch, Eugenia, Stiefelmaier, Judith, Lauer, Ira, Favilli, Lorenzo, Massner, Christoph, Öhrlein, Johannes, Grund, Bastian, Hüser, Andrea, Takors, Ralf, Blombach, Bastian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432763/
https://ncbi.nlm.nih.gov/pubmed/30962820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-019-1410-2
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