Motor cortex and pain control: exploring the descending relay analgesic pathways and spinal nociceptive neurons in healthy conscious rats

Motor cortex stimulation (MCS) is an effective therapy for refractory neuropathic pain. MCS increases the nociceptive threshold in healthy rats via endogenous opioids, inhibiting thalamic nuclei and activating the periaqueductal gray. It remains unclear how the motor cortex induces top-down modulati...

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Publicado en:Behav Brain Funct
Autores principales: Lopes, Patrícia Sanae Souza, Campos, Ana Carolina Pinheiro, Fonoff, Erich Talamoni, Britto, Luiz Roberto Giorgetti, Pagano, Rosana Lima
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432755/
https://ncbi.nlm.nih.gov/pubmed/30909927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12993-019-0156-0
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