Motor Cortex Stimulation Reversed Hypernociception, Increased Serotonin in Raphe Neurons, and Caused Inhibition of Spinal Astrocytes in a Parkinson’s Disease Rat Model

Persistent pain is a prevalent symptom of Parkinson’s disease (PD), which is related to the loss of monoamines and neuroinflammation. Motor cortex stimulation (MCS) inhibits persistent pain by activating the descending analgesic pathways; however, its effectiveness in the control of PD-induced pain...

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Veröffentlicht in:Cells
Hauptverfasser: Campos, Ana Carolina P., Berzuíno, Miriã B., Barbosa, Gabriela R., Freire, Helena M. R. C., Lopes, Patricia S., Assis, Danielle V., Fonoff, Erich T., Pagano, Rosana L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150310/
https://ncbi.nlm.nih.gov/pubmed/34064617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051158
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