Next-Generation Sequencing–Based Assessment of JAK2, PD-L1, and PD-L2 Copy Number Alterations at 9p24.1 in Breast Cancer: Potential Implications for Clinical Management

Genomic amplification at 9p24.1, including the loci for JAK2, PD-L1, and PD-L2, has recently been described as a mechanism of resistance in postchemotherapy, triple-negative breast cancer. This genomic signature holds significant promise as a prognostic biomarker and has implications for targeted th...

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Detalhes bibliográficos
Publicado no:J Mol Diagn
Main Authors: Gupta, Sounak, Vanderbilt, Chad M., Cotzia, Paolo, Arias-Stella, Javier A., Chang, Jason C., Zehir, Ahmet, Benayed, Ryma, Nafa, Khedouja, Razavi, Pedram, Hyman, David M., Baselga, José, Berger, Michael F., Ladanyi, Marc, Arcila, Maria E., Ross, Dara S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432425/
https://ncbi.nlm.nih.gov/pubmed/30576871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2018.10.006
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