Prostaglanin-E2 Potentiates the Suppressive Functions of Human Mononuclear Myeloid-Derived Suppressor Cells and Increases Their Capacity to Expand IL-10-Producing Regulatory T Cell Subsets

Myeloid-derived suppressor cells (MDSC) emerged as major factors driving the tumor progression due to numerous immunosuppressive mechanisms they possess. Prostaglandin (PG)E2 is shown critical for the induction of MDSC and their suppressive functions in vivo, but it is poorly understood how it affec...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Tomić, Sergej, Joksimović, Bojan, Bekić, Marina, Vasiljević, Miloš, Milanović, Marijana, Čolić, Miodrag, Vučević, Dragana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431635/
https://ncbi.nlm.nih.gov/pubmed/30936876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00475
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