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Selective Heteroaryl N-Oxidation of Amine-Containing Molecules

The first examples of nonenzymatic N-oxidation of heteroarenes in the presence of amines are reported. Pyridine, quinoline, and isoquinoline N-oxides are selectively formed in the presence of more reactive aliphatic and alicyclic amines by use of an in situ protonation strategy and an iminium salt o...

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Bibliographic Details
Published in:Org Lett
Main Authors: Dyer, Robert M. B., Hahn, Philip L., Hilinski, Michael K.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431535/
https://ncbi.nlm.nih.gov/pubmed/29547294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b00558
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