Allopurinol potentiates the hepatoprotective effect of metformin and vitamin E in fructose-induced fatty liver in rats

AIM OF THE STUDY: Non-alcoholic fatty liver disease (NAFLD) is a challenging health problem. Hyperuricemia is a key player in the pathogenesis of NAFLD. This study investigated the effect of allopurinol (uric acid synthesis inhibitor) in combination with metformin and vitamin E in prevention of fruc...

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Vydáno v:Clin Exp Hepatol
Hlavní autoři: Khalaf, Hanaa Mohamed, Ibrahim, Mohamed Abdellah, Amin, Entesar Farghaly, Abdel-tawab Ibrahim, Salwa, Abdel-Wahab, Soha, Fouad, Yasser Mahrous
Médium: Artigo
Jazyk:Inglês
Vydáno: Termedia Publishing House 2019
Témata:
Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431087/
https://ncbi.nlm.nih.gov/pubmed/30915409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/ceh.2019.83159
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