Targeted Expression of a Dominant-negative High Mobility Group A1 Transgene Improves Outcome in Sepsis

High mobility group (HMG) proteins are a family of architectural transcription factors, with HMGA1 playing a role in the regulation of genes involved in promoting systemic inflammatory responses. We speculated that blocking HMGA1-mediated pathways might improve outcomes from sepsis. To investigate H...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Baron, Rebecca M., Kwon, Min-Young, Castano, Ana P., Ghanta, Sailaja, Riascos-Bernal, Dario F., Lopez-Guzman, Silvia, Macias, Alvaro Andres, Ith, Bonna, Schissel, Scott L., Lederer, James A., Reeves, Raymond, Yet, Shaw-Fang, Layne, Matthew D., Liu, Xiaoli, Perrella, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431081/
https://ncbi.nlm.nih.gov/pubmed/29975792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4HI0817-333RR
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