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Water on hydrophobic surfaces: mechanistic modeling of polyethylene glycol-induced protein precipitation

For the purification of biopharmaceutical proteins, liquid chromatography is still the gold standard. Especially with increasing product titers, drawbacks like slow volumetric throughput and high resin costs lead to an intensifying need for alternative technologies. Selective preparative protein pre...

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Detalhes bibliográficos
Publicado no:Bioprocess Biosyst Eng
Main Authors: Großhans, Steffen, Wang, Gang, Hubbuch, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430756/
https://ncbi.nlm.nih.gov/pubmed/30535587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00449-018-2054-5
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