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Potassium channel selectivity filter dynamics revealed by single-molecule FRET
Potassium (K) channels exhibit exquisite selectivity for conduction of K(+) ions over other cations, particularly Na(+). High resolution structures reveal an archetypal selectivity filter (SF) conformation in which dehydrated K(+), but not Na(+), ions are perfectly coordinated. Using single molecule...
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| Veröffentlicht in: | Nat Chem Biol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6430689/ https://ncbi.nlm.nih.gov/pubmed/30833778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0240-7 |
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