Expression of MDM2 in Macrophages Promotes the Early Postentry Steps of HIV-1 Infection through Inhibition of p53

The molecular basis for HIV-1 susceptibility in primary human monocyte-derived macrophages (MDMs) was previously evaluated by comparing the transcriptome of infected and bystander populations. Careful analysis of the data suggested that the ubiquitin ligase MDM2 acted as a positive regulator of HIV-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Breton, Yann, Desrosiers, Vincent, Ouellet, Michel, Deshiere, Alexandre, Torresilla, Cynthia, Cohen, Éric A., Tremblay, Michel J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2019
Gaiak:
Virus-Cell Interactions
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430529/
https://ncbi.nlm.nih.gov/pubmed/30674627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01871-18
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