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Epstein-Barr Virus Nuclear Antigen 3C Augments Mdm2-Mediated p53 Ubiquitination and Degradation by Deubiquitinating Mdm2

Epstein-Barr virus (EBV) nuclear antigen 3C (EBNA3C) is one of the essential latent antigens for primary B-cell transformation. Previous studies established that EBNA3C facilitates degradation of several vital cell cycle regulators, including the retinoblastoma (pRb) and p27(KIP) proteins, by recrui...

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Detalhes bibliográficos
Main Authors: Saha, Abhik, Murakami, Masanao, Kumar, Pankaj, Bajaj, Bharat, Sims, Karen, Robertson, Erle S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668485/
https://ncbi.nlm.nih.gov/pubmed/19244339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02408-08
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