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Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities

The p53 tumor suppressor gene is one of the most commonly mutated genes in human cancers and the corresponding encoded protein induces apoptosis or cell-cycle arrest at the G1/S checkpoint in response to DNA damage. To date, previous studies have shown that antigens encoded by human tumor viruses su...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Yi, Fuming, Saha, Abhik, Murakami, Masanao, Kumar, Pankaj, Knight, Jason S., Cai, Qiliang, Choudhuri, Tathagata, Robertson, Erle S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287381/
https://ncbi.nlm.nih.gov/pubmed/19394062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.03.027
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