A dinuclear ruthenium(ii) phototherapeutic that targets duplex and quadruplex DNA

With the aim of developing a sensitizer for photodynamic therapy, a previously reported luminescent dinuclear complex that functions as a DNA probe in live cells was modified to produce a new iso-structural derivative containing Ru(II)(TAP)(2) fragments (TAP = 1,4,5,8-tetraazaphenanthrene). The stru...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Archer, Stuart A., Raza, Ahtasham, Dröge, Fabian, Robertson, Craig, Auty, Alexander J., Chekulaev, Dimitri, Weinstein, Julia A., Keane, Theo, Meijer, Anthony J. H. M., Haycock, John W., MacNeil, Sheila, Thomas, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430095/
https://ncbi.nlm.nih.gov/pubmed/30996941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05084h
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