Comparative sequence analysis of patient-matched primary colorectal cancer, metastatic, and recurrent metastatic tumors after adjuvant FOLFOX chemotherapy

BACKGROUND: In the era of genome-guided personalized cancer treatment, we must understand chemotherapy-induced genomic changes in tumors. This study evaluated whether adjuvant FOLFOX chemotherapy modifies the mutational profile of recurrent colorectal cancer (CRC). METHODS: Whole exome sequencing wa...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Harada, Kazuaki, Okamoto, Wataru, Mimaki, Sachiyo, Kawamoto, Yasuyuki, Bando, Hideaki, Yamashita, Riu, Yuki, Satoshi, Yoshino, Takayuki, Komatsu, Yoshito, Ohtsu, Atsushi, Sakamoto, Naoya, Tsuchihara, Katsuya
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429751/
https://ncbi.nlm.nih.gov/pubmed/30898102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5479-6
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