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Roles of SETD2 in Leukemia—Transcription, DNA-Damage, and Beyond
The non-redundant histone methyltransferase SETD2 (SET domain containing 2; KMT3A) is responsible for tri-methylation of lysine 36 on histone H3 (H3K36me3). Presence of the H3K36me3 histone mark across the genome has been correlated with transcriptional activation and elongation, but also with the r...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6429614/ https://ncbi.nlm.nih.gov/pubmed/30818762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051029 |
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