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Folate Repletion after Deficiency Induces Irreversible Genomic and Transcriptional Changes in Human Papillomavirus Type 16 (HPV16)-Immortalized Human Keratinocytes

Supplementation of micronutrients like folate is a double-edged sword in terms of their ambivalent role in cell metabolism. Although several epidemiological studies support a protective role of folate in carcinogenesis, there are also data arguing for an opposite effect. To address this issue in the...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Savini, Claudia, Yang, Ruwen, Savelyeva, Larisa, Göckel-Krzikalla, Elke, Hotz-Wagenblatt, Agnes, Westermann, Frank, Rösl, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429418/
https://ncbi.nlm.nih.gov/pubmed/30836646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051100
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