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Development of Anthraquinone Analogues as Phosphoglycerate Mutase 1 Inhibitors
Phosphoglycerate mutase 1 (PGAM1) coordinates glycolysis and biosynthesis to promote cancer cell proliferation, and is believed to be a promising target for cancer therapy. Herein, based on the anthraquinone scaffold, we synthesized 31 anthraquinone derivatives and investigated the structure−activit...
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| Yayımlandı: | Molecules |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
MDPI
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6429356/ https://ncbi.nlm.nih.gov/pubmed/30818883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24050845 |
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