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The Design and Synthesis of N-Xanthone Benzenesulfonamides as Novel Phosphoglycerate Mutase 1 (PGAM1) Inhibitors

Upregulation of phosphoglycerate mutase 1 (PGAM1) has been identified as one common phenomenon in a variety of cancers. Inhibition of PGAM1 provides a new promising therapeutic strategy for cancer treatment. Herein, based on our previous work, a series of new N-xanthone benzenesulfonamides were disc...

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Опубликовано в: :Molecules
Главные авторы: Wang, Penghui, Jiang, Lulu, Cao, Yang, Ye, Deyong, Zhou, Lu
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100356/
https://ncbi.nlm.nih.gov/pubmed/29890679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061396
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