Down-Regulation of Astrocytic Kir4.1 Channels during the Audiogenic Epileptogenesis in Leucine-Rich Glioma-Inactivated 1 (Lgi1) Mutant Rats

The dysfunction of astrocytic inwardly rectifying potassium (Kir) 4.1 channels, which mediate the spatial potassium-buffering function of astrocytes, is known to be involved in the development of epilepsy. Here, we analyzed the Kir4.1 expressional changes in Leucine-Rich Glioma-Inactivated 1 (Lgi1)...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Kinboshi, Masato, Shimizu, Saki, Mashimo, Tomoji, Serikawa, Tadao, Ito, Hidefumi, Ikeda, Akio, Takahashi, Ryosuke, Ohno, Yukihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429235/
https://ncbi.nlm.nih.gov/pubmed/30813600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051013
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