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Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of (68)Ga-Labeled Tracers
Affibody-based imaging of HER3 is a promising approach for patient stratification. We investigated the influence of a hydrophilic HEHEHE-tag ((HE)(3)-tag) and two different gallium-68/chelator-complexes on the biodistribution of Z(08698) with the aim to improve the tracer for PET imaging. Affibody m...
Shranjeno v:
| izdano v: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6429182/ https://ncbi.nlm.nih.gov/pubmed/30832342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051080 |
| Oznake: |
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