Increase in negative charge of (68)Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules

Upregulation of the human epidermal growth factor receptor type 3 (HER3) is a common mechanism to bypass HER-targeted cancer therapy. Affibody-based molecular imaging has the potential for detecting and monitoring HER3 expression during treatment. In this study, we compared the imaging properties of...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Rinne, Sara S., Dahlsson Leitao, Charles, Gentry, Joshua, Mitran, Bogdan, Abouzayed, Ayman, Tolmachev, Vladimir, Ståhl, Stefan, Löfblom, John, Orlova, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881397/
https://ncbi.nlm.nih.gov/pubmed/31776413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54149-3
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky